Categories: world

Stella safeguards the oocyte methylome by preventing the novo methylation mediated by DNMT1

1. Shirane, K. et al. Mouse oocyte methylomes at base resolution reveal genomic-wide accumulation of non-CpG methylation and role of…

  • 1.

    Shirane, K. et al. Mouse oocyte methylomes at base resolution reveal genomic-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet . 9 e1003439 (2013).

  • 2.

    Smallwood, S.A. et al. Dynamic CpG island methylation landscape in oocytes and preimplantation embryos. Nat. Genet . 43 81

    1-814 (2011).

  • 3.

    Stewart, K. R., Veselovska, L. & Kelsey, G. Establishment and functions of DNA methylation in the germline. Epigenomics 8 1399-1413 (2016).

  • 4.

    Kobayashi, H. et al. Contribution of intravenic DNA methylation into mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet . 8 e1002440 (2012).

  • 5.

    Nakamura, T. et al. PGC7 / Stella protects against DNA demethylation in early embryogenesis. Nat. Cell Biol . 9 64-71 (2007).

  • 6.

    Bortvin, A., Goodheart, M., Liao, M. & Page, DC Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice. BMC Dev. Biol . 4 2 (2004).

  • 7.

    Payer, B. et al. Stella is a maternal effect gene required for normal early development in mice. Curr. Biol . 13 2110-2117 (2003).

  • 8.

    Sharif, J. et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450 908-912 (2007).

  • 9.

    Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317 1760-1764 (2007).

  • 10.

    Sato, M. et al. Identification of PGC7 a new gene expressed specifically in preimplantation embryos and germ cells. Mech. Dev . 113 91-94 (2002).

  • 11.

    Saitou, M., Barton, S.C. & Surani, M.A. A molecular program for the specification of germ cell fate in mice. Nature 418 293-300 (2002).

  • 12.

    Funaki, S. et al. Inhibition of maintenance DNA methylation by Stella. Biochem. Biophys. Res. Commun . 453 455-460 (2014).

  • 13.

    Maenohara, S. et al. Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos. PLoS Genet . 13 e1007042 (2017).

  • 14.

    Huang, Y. et al. Stella modulates transcriptional and endogenous retrovirus programs during maternal to zygotic transition.

    eLife 6 e22345 (2017).

  • 15.

    Shin, SW, Vogt, EJ, Jimenez-Movilla, M., Baibakov, B. & Dean, J. Cytoplasmic cleavage or DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat. Commun . 8 1643 (2017).

  • 16.

    Bourc’his, D., Xu, GL, Lin, CS, Bollman, B. & Bestor, TH Dnmt3L and the establishment of maternal genomic imprints. Science 294 2536-2539 (2001).

  • 17.

    Kaneda, M. et al. Essential role for the novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429 900-903 (2004).

  • 18.

    Nakamura, T. et al. PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature 486 415-419 (2012).

  • 19.

    Han, L. et al. Embryonic defects induced by maternal obesity in mice derive from stella insufficiency in oocytes. Nat. Genet . 50 432-442 (2018).

  • 20.

    Li, Y. & O’Neill, C. 5′-Methylcytosine and 5′-hydroxymethylcytosine each provide epigenetic information to the mouse zygote.

    PLoS ONE 8 e63689 (2013).

  • 21.

    Bestor, TH & Ingram, VM Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA. Proc. Natl Acad. Sci. USA 80 5559-5563 (1983).

  • 22.

    Goto, K. et al. Expression of DNA methyltransferase genes in mature and immature neurons as well as proliferating cells in mice. Differentiation 56 39-44 (1994).

  • 23.

    Arand, J. et al. In vivo control of CpG and non-CpG DNA methylation at DNA methyltransferases.

    PLoS Genet 8 e1002750 (2012).

  • 24.

    Lorincz, MC, Schübeler, D., Hutchinson, SR, Dickerson, DR & Groudine, M. DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a / b-independent de novo methylation. Mol. Cell. Biol . 22 7572-7580 (2002).

  • 25.

    Vertino, PM, Yen, RW, Gao, J. & Baylin, SB De novo methylation or CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5 -) methyltransferase. Mol. Cell. Biol . 16 4555-4565 (1996).

  • 26.

    Takagi, H., Tajima, S. & Asano, A. Overexpression or DNA methyltransferase in myoblast cells accelerates myotube formation. Eur. J. Biochem . 231 282-291 (1995).

  • 27.

    Tiscornia, G., Singer, O. & Verma, I. M. Production and Purification of Lentiviral Vectors. Nat. Protoc . 1 241-245 (2006).

  • 28.

    de Vries, W.N. et al. Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes. Genesis 26 110-112 (2000).

  • 29.

    Jackson-Grusby, L. et al. Loss or genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat. Genet . 27 31-39 (2001).

  • 30.

    Gu, T.P. et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477 606-610 (2011).

  • 31.

    Rothbauer, U. et al. A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Mol. Cell Proteomics 7 282-289 (2008).

  • 32.

    Qin, W. et al. Efficient CRISPR / Cas9-mediated genomic editing in mice by zygote electroporation of nuclease.

    Genetics 200 423-430 (2015).

  • 33.

    Hashimoto, M. & Takemoto, T. Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR / Cas9-based genomic editing. Sci. Rep . 5 11315 (2015).

  • 34.

    Bock, C. et al. BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics 21 4067-4068 (2005).

  • 35.

    Yin, R. et al. Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J. Am. Chem. Soc . 135 10396-10403 (2013).

  • 36.

    Boyle, P. et al. Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling. Genome Biol . 13 R92 (2012).

  • 37.

    Gu, H. et al. Preparation of reduced representation of bisulfite sequencing libraries for genomic scale DNA methylation profiling. Nat. Protoc . 6 468-481 (2011).

  • 38.

    Shen, L. et al. Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes. Cell Stem Cell 15 459-471 (2014).

  • 39.

    Krueger, F. & Andrews, SR Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications . Bioinformatics 27 1571-1572 (2011).

  • 40.

    Illingworth, R. S. et al. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet . 6 e1001134 (2010).

  • 41.

    Krueger, F. & Andrews, S. R. SNPsplit: Allele-specific cleavage or alignments between genomes with known SNP genotypes. F1000Res . 5 1479 (2016).

  • Share
    Published by
    Faela