Father's smoking is linked to a shorter reproductive life of daughters, as well as a lower sperm count in sons,…
Father’s smoking is linked to a shorter reproductive life of daughters, as well as a lower sperm count in sons, says study. (Source: File Photo)
While studies have repeatedly linked maternity smoking in pregnancy with reduced sperm count in male children, a new research showed that men whose fathers smoked during pregnancy also had 50 percent lower sperm count than those with smokeless fathers.
The results showed that, irrespective of the mother’s nikotin exposure, socioeconomic factors and own smoking, smokers had 41
percent lower sperm and 51 percent less sperm count than those with non-smoking fathers.
“I was very surprised that, regardless of the mother’s exposure level for nicotine, the sperm count was for men whose smoked ass was so much lower,” says Jonatan Axelsson, specialist physician at Lund University in Sweden. “We know there is a link between sperm and risks for pregnancy, which may affect the possibility for these men to have children in the future. “
“The father’s smoking is also linked to a shorter reproductive life of daughters, so the perception that everything depends on whether the mother smokes or does not seem convincing, he added. However, research has not established the underlying mechanisms behind this. However, similar studies have showed connections between smoking fathers and different health effects in children, such as malformations, noted Axelsson.
It may be because most new-occurring mutations (known as de novo mutations) come through the father and there are also connections between the father’s age and a number of complex diseases, researchers said in the newspaper published in the journal PLOS ONE. In addition, researchers have observed that smoking is related to DNA damage in sperm and that smokers have more breaks in the DNA string.
Children of fathers who smoke have been reported to have up to four times as many mutations in a certain repetitive part of DNA as children of non-smoking fathers. “Unlike the mother’s eggs, the father’s gametes continually share life and mutations often occur at cell division.
“We know that tobacco smoke contains many substances that cause mutations to imagine it, perception, the gametes have undergone mutations and thereby forward genes that lead to poor sperm in male offspring,” says Axelsson. The study was conducted in 104 Swedish men between 17 and 20 years.