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Some children with acute sleepmymyitis (AFM) in polio-like disease may be diagnosed with the disease, “says a doctor.

There is a good chance that some cases of the Mystical Polio-like Disease recently seen in American children may have…

There is a good chance that some cases of the Mystical Polio-like Disease recently seen in American children may have been diagnosed, a new study report.

Acute Leak Myelitis (AFM) which causes potentially life-threatening paralysis and primarily strikes children, has returned to the United States in every two year’s waves since 2014.

However, it is likely that some children diagnosed with AFM actually has any other neurological disorder. And it is equally possible that some true cases of AFM are missed, “says Dr. Matthew Elrick, a childish neurologist with Johns Hopkins University in Baltimore.

“This is a challenging diagnosis,” says research scientist Elrick. “There are overlaps with other diseases.”

His team reviewed 45 children who met the British federal definition of AFM and found that 1

1 actually suffered from other neurological diseases.

Elrick and his colleagues believe they have identified specific symptoms that clearly indicate AFM, based on the group of children they studied.

It is important to arrive at a more precise definition because AFM is “a major public health problem that we really need to focus on,” said Elrick.

Until 2018, the US Center for Disease Control and Prevention has confirmed 116 cases of AFM of a total of 286 reports investigated. These cases have occurred in 31 US states.

This is the third wave of AFM to hit the United States, and it is expected to be the biggest on record.

AFM appeared in 2014 only when 120 children over 34 states became subject to mysterious muscle weakness .

Another wave battle in 2016, with 149 patients affected in 39 states.

“During the first outbreak of 2014, there was a kind of curiosity we hoped was a single thing, but it is now established a pattern that will return 2016 and 2018 with higher numbers each time,” said Elrick. “There is plenty of reason to be concerned that there may be another outbreak in 2020 and beyond. “

The new study, published November 30th in the journal JAMA Pediatrics found that children with a certain AFM share had several characteristics

  • All children with more restrictively defined AFM had a viral infection that preceded their weakness.
  • These children all shared similar readings on MRI scans, spinal fluid tests and electromyography (a test of muscle’s electrical activity tissue).
  • All the children had a pattern of muscle weakness indicating damage to the lower motor neurons, which are nerve cells in the spinal cord that initiate muscle contraction.

“They were not only weak but also their muscles Their tone was reduced and their reflexes were reduced or absent, “said Elrick.

A few other symptoms may indicate AFM but are not crucial, allow the researchers.

Almost all cases of AFM begin asym Metric, with one side of the body more affected than the other, Elrick said. However, this can not be used to exclude AFM in a child with symmetrical muscle weakness.

Timing can also be important. “The symptoms are relatively sudden but then progressively progressing over the hours to days, where some of the other cases have this very quick start,” said Elrick.

On the other hand, there are some symptoms that should encourage doctors to consider diagnosing other than AFM, the researchers said.

Parents with AFM usually do not lose the feeling or feeling beside their paralysis paralysis . They tend to wake up and warn, and MRI scans show no signs of brain damage, said Elrick.

“I would not necessarily say that a child who does not meet these criteria at the hospital absolutely does not have AFM, but it would at least make me pause and go back and rethink alternative diagnoses,” said Elrick.

The CDC established a broad fall definition for AFM, so the agency’s epidemiologists could gather as many potential cases as possible for evaluation, said Elrick. Of these, a small number will be confirmed.

But when it comes to finding a treatment or cure for AFM, researchers must be very more accurate when choosing patients to study, said Elrick. That way they will know they are working with someone who has the actual disease.

“This is a step forward for defining these patients in a research setting, but also gives some guidance in a clinical environment, “said Elrick

It is really very possible that some AFM cases are diagnosed,” says Dr Ril Ey Bove, a neurologist with the University of California, San Francisco.

“I sometimes know that presentations in children may overlap. Conditions can cause spinal cord injury,” says Bove, who wrote a perspective that followed Elrick’s study.

Bove son, 8 year old Luca, developed AFM during the first wave of 2014 and shares characteristics identified by Elricks research team.

The boy got sick with a virus that went through his home and school and recovered from it, Bove said.

“About 10 days later he woke up and his head fell back, and he said he was dizzy and could not sit straight,” said Bove. “During the day his neck and right arm became paralyzed.”

He further worsened during the next week, losing all muscle function from the face downwards. At one point, Lucas paralysis became so deep that he needed help with breathing and feeding, said Bove.

The boy went out of rehab “very floppy and weak” two months later, said Bove.

“He still has stingy weakness in most parts of the body, especially his right arm and neck and shoulder,” Bove said. “He must learn to write left handed. He has the classic diskette, shiny, short little limb with polio. “

Still worried parents should remember that this is” really rare, “says Bove.

But because it is a rare condition, parents should be prepared to drive their doctors hard if their children develop muscle weakness after a virus infection, she added.

“Parents really need to be advocates here, because the condition is rare and it is badly aware of it,” says Bove. “If a parent notices unusual symptoms in their children, really be persistent that they have been evaluated.”

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