In Parkinson's patients, the song can help improve mood and motor symptoms and reduce physiological stress indicators, according to the…
In Parkinson’s patients, the song can help improve mood and motor symptoms and reduce physiological stress indicators, according to the preliminary results of a new pilot study at Iowa State University (ISU).
The research presented at the Society for the Neuroscience 2018 conference is based on the team’s previous discoveries that singing is an effective treatment for improving breathing regulation and the muscles used to swallow in Parkinson’s patients.
Elizabeth Stegemöller, professor of kinesiology at Iowa State University, says that although the result is preliminary, the improvements among singing participants are similar to those seen with medication.
“We see improvement every week when they leave a group of singles. It’s almost as if they have a little pep in their step.” We know they feel better and their mood is enhanced, “Stegemöller says.
” Some of the symptoms which improves, for example, fingertip and time, does not always respond easily to the medicine, but by singing they are “improved.”
Stegemöller conducted the study with Elizabeth “Birdie” Shirtcliff, a lecturer in family studies in human development and Andrew Zaman, a doctoral student in kinesiology. The team measured heart rate, blood pressure and cortisol levels for 1
7 participants in a therapeutic vocal group.
The participants reported themselves feelings of sorrow, anxiety, happiness and anger. The data was collected before and after an hour’s session.
The study is one of the first to look at how song affects heart rate, blood pressure and cortisol in people with Parkinson’s disease. Although all three levels were reduced among patients in the study, Stegemöller said that the preliminary data did not reach statistical significance. And while there were no significant differences in happiness or anger after class, the participants were less keen and sad.
The findings are encouraging, but researchers still have a big question to deal with: What is the mechanism that leads to these behavioral changes? 19659002] The team is now analyzing blood samples to measure levels of oxytocin (a hormone related to binding), changes in inflammation (an indicator of disease progression) and neuroplasticity (brain’s ability to compensate for injury or disease) to determine whether these factors can explain the benefits singing.
“Part of the reason that the cortisol goes down may be because the singing participants feel positive and less stressed in the song with others in the group. This suggests that we can look at the binding hormone, oxytocin,” says Shirtcliff.  “We also look at heart rate and heart rate variation, which can tell us how calm and physiologically relaxed the individual is after singing.”  The spread of Parkinson’s disease is expected to double over the next 20 years. The researchers say that therapeutic vocals can be an accessible, affordable treatment option that helps improve symptoms, stress and quality of life for people with Parkinson’s disease.
Source: Iowa State University