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“Novel 3D bioprinting tech to create artificial blood vessels, organ tissue”

Researchers have developed a 3D printing technique that can restore the complex geometry of blood vessels and could one day…

Researchers have developed a 3D printing technique that can restore the complex geometry of blood vessels and could one day be used to produce artificial arteries and organ tissues.

A study, published in the journal Nature Communications, outlines a layer of in-stock printing method that has fine grains, programmable control over stiffness.

The result can lead to better and more personal treatments for people suffering from high blood pressure and other vascular diseases.

“The idea was to add independent mechanical properties to 3D structures that resemble the body‘s natural tissue,” said Xiaobo Yin, a professor at the University of Colorado (CU) Boulder in the United States.

“This technology allows us to create microstructures that can be adapted for disease models,” says Yin.

Hardened blood vessels are associated with cardiovascular disease, but constructing a solution for viable arterial and tissue replacement has historically proved challenging.

In order to overcome these obstacles, researchers have found a unique way to take advantage of the acid screen in determining the final form of a 3D-printed structure.

“Oxygen is usually a bad thing because it causes incomplete cure. Here we use a layer that allows for a fixed rate of oxygen permeation,” says Yonghui Ding, a postdoctoral researcher at CU Boulder.

By retaining control over oxygen migration and its subsequent exposure to light, researchers have the freedom to control which areas of an object stiff to be harder or softer &#821

1; while keeping the overall geometry the same.

“This is an in-depth development and an encouraging first step towards our goal of creating structures that work as a healthy cell will work,” said Ding.

As a demonstration, the researchers pushed a small Chinese war figure so that the outer layers were difficult while the interior was soft.

The printer with the writing platform can currently work with biomaterials down to a size of 10 microns or about one tenth width of a human hair. 19659002] The researchers are optimistic that future studies will help improve capacity further.

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