Researchers have designed a portable and inexpensive diagnostic tool that uses a mobile phone and nanotechnology that can detect HIV…
Researchers have designed a portable and inexpensive diagnostic tool that uses a mobile phone and nanotechnology that can detect HIV and monitor its management in resource-limited regions.
Human Immunodeficiency Virus 1 (HIV), a disorder that paralysis the immune system by attacking healthy cells, remains a major global health challenge in developing countries without infrastructure and trained healthcare professionals.
“Early detection of HIV is crucial for preventing disease progression and transmission, and it requires long-term monitoring, which can be a burden for families who have to travel to clinics or hospitals,” said Hadi Shafiee from Brigham and Women’s Hospital in the United States.
“This fast and cheap mobile phone system represents a new method of detecting acute infection, which would reduce the risk of virus transmission and can also be used to detect early treatment failure,” said Shafiee
. Traditional virus monitoring methods for HIV are expensive, which requires Use of Polymerase Chain Reaction (PCR) according to the study published in the journal Nature Communications.
Shafiee and his colleagues designed an affordable and easy tool that enables HIV testing and monitoring for individuals in developing countries with less access to medical care.
Using nanotechnology, microchip, cell phone and a 3D printing esearchers created a platform that can detect the virus’s RNA nucleic acids from a single drop of blood.
The device detects the amplified HIV nucleic acids by phone monitoring the movement of DNA-constructed beads without using bulky or expensive equipment.
Detection accuracy was evaluated for specificity and sensitivity.
Researchers found that the platform enabled detection of HIV with 99.1
percent specificity and 94.6 percent sensitivity at a clinically relevant threshold of 1000 virus particles / mililiter, with results within one hour.
The total material cost of microchip, telephone collection and reagents was less than USD 5 per test, researchers said.
“Health professionals in developing countries can easily use these devices when they travel to perform HIV testing and monitoring. As the test is so fast, critical decisions about the next medical step can be done there, Shafiee said.
” This would eliminate the burden of travels to the medical clinic and give individuals a more effective means of managing their HIV, “said Shafiee.
” We could use the same technology as a fast and cheap diagnostic tool for other viruses and bacteria too, “said Mohamed Shehata Draz from Brigham and Women’s Hospital.
“This platform can help many people worldwide,” said Draz.
(This story has not been edited by Business Standard staff and is automatically generated from syndicate feed.)