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Low Temp, Low Pressure, and High Wind Tied to MI Risk

A range of weather conditions was linked to increased risk of myocardial infarction (MI), a large, prospective, population-based study from…

A range of weather conditions was linked to increased risk of myocardial infarction (MI), a large, prospective, population-based study from Swedish found.

MI occurrence varied depending on the air temperature, atmospheric air pressure, wind speed, and hours of sunshine on a given day. The most obvious relationship was for air temperature, in which a 1 standard deviation (SD) rise (7.4 ° C or 13.32 ° F) was linked with a 2.8% decrease in MI risk (unadjusted incidence rate ratio 0.972, 95% CI 0.967 <0.001), reported David Erlinge, MD, PhD, or Lund University in Sweden tussen colderklimaten en MI-risico, de onderzoekers opgemerkt, maar deze papieren hebben reliëf op surrogaatvariabelen “als indicatoren van MI, en veel studies hebben alleen maar gezien bij lucht temperatuur en sneeuw; andere meteorologische parameters hebben niet zo veel onderzocht.”

De doelstelling van de huidige studie was om te beoordelen alle weersparameters en incidentie van MI, “door het combineren van klinische data met weersstation meteorologische variabelen verzameld in de nabijheid van coronaire zorgunits (CCU’s),” zodat de auteurs kunnen “onderzoeken de verenigingen van alle major weather parameters a nd risk of MI. “

These findings are” consistent with previous studies showing that heart attacks appear to occur more frequently in the more extreme weather, especially in cold winter weather, “said Kim Eagle, MD, of the University of Michigan in Ann Arbor, who was not involved in the study.

“We think that the coronary arteries may have less vasodilator reserve in the cold or for diseased segments, may even constrict in the cold which may be associated with coronary artery plaque rupture, “Eagle noted to MedPage Today .

The researchers evaluated 274,029 MI patients, with a mean age of 71

.2 in Sweden. Erlinge’s group collected meteorological data and merged it with each MI based on the date the symptom first occurred and CCU.

For air pressure (kilopascal or kPa) and sunshine duration, a 1-SD increase in each was associated with a reduced risk or MI:

  • Air pressure 10.9 kPa: adjusted IRR 0.987 (95% CI 0.981-0.993, P <0.001)
  • Sunshine duration 4.2 hours: unadjusted IRR 0.987 (95% CI 0.983-0.992 , P <0.001)

A 1-SD increase in wind velocity (1.9 m / s) was associated with an increased risk of MI (adjusted IRR 1.012, 95% CI 1.005-1.018, P <0.01).

Even within a relatively localized geographical area these changes are noticeable, noted Robert Bonow, MD, or Northwestern Memorial Hospital in Chicago. Men, disse resultatene kan eller ikke være generelle, som kan være til nogen som bor i Italien, “Bonow said.

En anden begrænsning af studien er at det ikke er meget actionabelt; Det er vanskelig å gøre interventioner baseret på disse resultater, bemærkede Bonow, men han tilføjede at det er vigtigt for patienter med hjertesygdomme, og deres caregivere, at de er tider af året når der er større risici.

Clinicians prefer Patients to exercise in hot weather, and generally advise patients with known coronary disease to be wary of doing intense exercise in cold weather, noted Eagle. “If they do shovel or snow blow, [we]they prefer wearing a scarf over their nose and mouth to warm the air before it hits the lungs. Patients should definitely warm up and cool down if they exercise in the cold.” [19659015] The study supported by the Swedish Heart and Lung Foundation, the Swedish Scientific Research Council, the Swedish Foundation for Strategic Research (TOTALAMI), the Knut and AliceWallenberg Foundation, Medical Doctorate and Research (ALF), and Skane University Hospital.

Erlinge and Bonow disclosed no relevant relationships with industry.

Eagle disclosed relevant relationships with Gore and Medtronic.

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