This is Frankenstein's breakthrough that the medical world has long feared. A Chinese scientist declared yesterday that he has changed…
This is Frankenstein’s breakthrough that the medical world has long feared. A Chinese scientist declared yesterday that he has changed the basic genetic code for human children, using methods prohibited in most of the world.
The potential consequences are as alarming as they are unpredictable. No less an authority than Professor Stephen Hawking was afraid of such experiments would one day create a race of “super people” and end humanity as we know.
Researchers have already discovered that redirection can cause a variety of cancers to interfere with a genetic code so complicated, we may never be able to comprehend it completely.
Professor He Jiankui used CRISPR editing to change the basic genetic code for human babies (movie image)
The worst news of all? The technology used by the Chinese scientist is so cheap and simple that it can rub a world where someone would be angry professor can write about life’s life plan without respecting the risks.
Of course, the researcher, He Jiankui, professor of biology at China’s Southern University of Science and Technology, describes this not.
He claims he is in charge of a medical breakthrough that can make newborn immune to infection with the HIV virus. He did, he said, using a groundbreaking technique called CRISPR (or Crispr-Cas9 to give it his full name) to change the children’s DNA before they were born.
CRISPR editing was invented six years ago. It uses an enzyme that acts as a pair of scissors, snipping out defective genes, either in embryos or adults, and then putting “healthy” genetic material into the gaps.
The United Kingdom, the United States and other leading nations have all banned the use of CRISPR editing in unborn children because the changes can not be reversed and can also be inherited by future generations.
If the genetically altered Chinese children survive to have children, Professor Han is a mutant gene – with all irreversible dangers – could infect humanity forever.
Nevertheless, the professor could go on with his efforts – obviously without even telling his university employees. He revealed his work for the first time only on Sunday at a Hong Kong reconsideration conference.
He said that he changed embryos of seven couples who perform fertility treatment, one of which has since given birth to twin girls.
The professor tried to disable a gene that creates a vital part of the human immune system called CCR5, a protein that is located on the outside of our immune cells. The HIV virus uses the CCR5 gene as a vulnerable wire through which it can enter these immune cells, so it can infect and paralyze the body’s defense. By erasing this gene, he tells us that he has made the twins harmless to HIV.
Professor He is tinkering, thus giving his twins a dangerous false sense of security; Worse, it can condemn them to early death from infections.
It has been known for more than a decade that people born with CCR5 deficiency have endangered the immune system and face risk of dying of the flu and western virus. 19659002] More chilling still, we also know CRISPR editing is filled with other unintentionally lethal consequences.
In June, two articles in the journal Nature warned that patients treated under other conditions, CRISPR editing can cause ovarian, lung, breast, liver and intestinal cancer. In August, researchers at the well-known Wellcome Sanger Institute in Cambridgeshire reported that when specific genes in cells from humans and mice were edited, it left a mess of missing and moving DNA parts whose consequences could be catastrophic.
Professor He’s announcement is the realization of fear of respectful scientists as CRISPR editing can open the gates into a world of “Frankenstein’s Garden Hall”. Professor Charis Thompson, a genetic ethics expert at the London School of Economics, has warned that even ranks amateurs can start playing with the technology with “relative ease”.
Actually, Professor Han has no experience of running human clinical trials, left none of his work to the ethical and medical review that is crucial in this area and has not even published his research in a scientific journal where it would have been appreciated by other experts.
Instead, he says that he is practiced by genetic engineering genes of mice, monkeys and human embryos in his lab before trying for real human children and has already established two genetics companies and applied for patents on their dubious methods.
CRISPR work on human embryos is allowed in China. But Professor He is university administrators say they have not been aware of his business.
At the same time, responsible scientists carefully investigate how remediation can provide much needed cures for human disease while trying to avoid disaster.
Already around 2700 clinical trials with CRISPR therapies are ongoing or approved around the world, aimed at combating diseases as diverse as cancer, muscle dystrophy and sickle cell anemia. Some genuine breakthroughs have been made. Last year, surgeons at Great Ormond Street announced that they had used redirection to treat a child with lymphoblastic leukemia, a form of disease that is otherwise unbearable.
DNA editing is also used to reverse cancer patients immune cells to a targeted killer army that, when injected back into the body, can destroy tumors.
All such work is performed in infants and adults, not fetuses. Many common scientists are convinced that the love of unborn people is too uncertain to ever try.
One of Britain’s most famous researchers from beyond the grave also warned that we would abandon this science area forever – or risk destroying humanity.
Last month, a posthumously published paper by Professor Hawking predicted to tinker with our own DNA, we are on the brink of creating a genetically modified championship that can dry us out.
Mayhem would be released, predicted by people choosing to edit and improve their and their children’s DNA. 19659002] “When such superhumans appear to be significant problems with the relentless people who are likely to die, he predicted.” Instead, there will be a race of self-designing creatures that are improving at an ever increasing rate. “ Chinese researchers have already taken the first step by creating dogs with super muscles to make them better for police work.
We only have two hopes. The more immediate is what British experts suggest, Professor He is just showboating and his work will eventually come to nothing.
In the long run, humanity must agree on a complete global moratorium on redevelopment experiments on unborn children. This is the only way to provide proper protection against the potentially catastrophic consequences .
Whether it is real or not, Professor Hans’s statement is an alarm clock that warns us all of the fatal threat of Frankenstein’s involvement. If this alarm resolves, the future of our future can be at risk.