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Innovative malaria vaccine for children to be tested in Malawi

Image copyrightD Poland / PATH CaptionThe vaccine has already been tested in smaller test programs A large-scale trial of what has been called the world's first malaria vaccine to provide partial protection to children is due to begin in Malawi. The RTS, S vaccine trains the immune system to attack the malaria parasite, which was spread by mosquito bites. Previously, minor trials showed that nearly 40% of the 5 to 1 7 year olds who received it were protected. Malaria cases appear to be rising again after a decade of success in the fight against the lethal disease. According to the latest annual figures, global malaria issues no longer fall, giving rise to concern over their resurgence. SPL Malaria in 2017 [19659014] Source: WHO More than 90% of those infected and the 435,000 who died were killed in Africa. Children are particularly vulnerable. Malawi saw nearly five million confirmed cases in 2017 and it has been selected together with Kenya and Ghana to be used in large-scale pilot of the RTS, S vaccine. Three Decades of Development The countries were picked because they are already running large programs to deal with malaria, including the use of bed nets, but still have a large number of cases. The vaccine has been running more than three decades with Scientists from the pharmaceutical company GSK created it in 1987. The year of testing supported by a variety of organizations, including the path malaria vaccine initiative, costs about $ 1 billion (£ 770 million…

 Vaccine given

Image copyright
D Poland / PATH

Caption

The vaccine has already been tested in smaller test programs

A large-scale trial of what has been called the world’s first malaria vaccine to provide partial protection to children is due to begin in Malawi. The RTS, S vaccine trains the immune system to attack the malaria parasite, which was spread by mosquito bites.

Previously, minor trials showed that nearly 40% of the 5 to 1

7 year olds who received it were protected.

Malaria cases appear to be rising again after a decade of success in the fight against the lethal disease.

According to the latest annual figures, global malaria issues no longer fall, giving rise to concern over their resurgence.

SPL

Malaria in 2017 [19659014] Source: WHO

More than 90% of those infected and the 435,000 who died were killed in Africa. Children are particularly vulnerable.

Malawi saw nearly five million confirmed cases in 2017 and it has been selected together with Kenya and Ghana to be used in large-scale pilot of the RTS, S vaccine.

Three Decades of Development

The countries were picked because they are already running large programs to deal with malaria, including the use of bed nets, but still have a large number of cases.

The vaccine has been running more than three decades with Scientists from the pharmaceutical company GSK created it in 1987.

The year of testing supported by a variety of organizations, including the path malaria vaccine initiative, costs about $ 1 billion (£ 770 million ) has led to this point.

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Getty Images

Captions

Campaigns have long required an effective way to deal with malaria

The latest phase is coordinated by the World Health Organization (WHO), which states that the vaccine is the first to provide some protection for children.

The closest 40% effect is not high compared to vaccines for other diseases, but the WHO says that RTS, S will add preventive measures, such as bed nets and insecticides, already used, reports from AFP’s news agency.

“A vaccine that is very effective, 90% or so, is not in sight at this point,” WHO’s Mary Hamel is quoted by Bloomberg as said. “But this vaccine comes to that where it is found that a malaria vaccine can be made. It will be a seeker.”

The vaccine must be given four times – once a month for three months and then a fourth dose 18 months later.

This stage of the experiment is expected to be completed in 2023 according to Path.

The pilot starts in Malawi and will start in Kenya and Ghana in the next few weeks.

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