Children developing inflammatory bowel disease – ulcerative colitis or Crohn's disease – are at increased risk of death, both in…
Children developing inflammatory bowel disease – ulcerative colitis or Crohn’s disease – are at increased risk of death, both in childhood and later in life, according to a new study.
Inflammatory bowel disease (IBD) is the ongoing inflammation of all or part of the digestive system.
The results of the study suggested that it is important that patients diagnosed with IBD are carefully monitored.
“Persons diagnosed in childhood must be carefully monitored,” says Ola Olén, senior researcher at Karolinska Institutet in Sweden.
For the study, published in the journal Gastroenterology, the group compared the severity of mortality in about 9,400 children who developed inflammatory bowel disease with other children.
They also identified patients with IBD, such as ulcerative colitis and Crohn’s disease.
The results showed that children who developed IBD before the age of 18 have a 3-5 times higher mortality than people without IBD during childhood and adulthood.
This explains a 2.2-year reduction in life expectancy in individuals monitored up to 65 years of age. The result was suggested.
“Most young people with IBD do not die sooner than their comrades, but some individuals with a severe fall of IBD and severe complications such as cancer greatly increase the relative risk,” says Olén.
The most common cause of death was cancer, while deaths due to IBD itself represented the largest relative increase in mortality.  IBD in adults has previously been linked to shortened life and is often considered to have a more aggressive disease course among children compared with adults.
However, it has been unclear how Life expectancy is affected by IBD and if mortality has changed since the introduction of modern drugs.
| Edited by: Naqshib Nisar