Women working close to busy roads are at high risk of developing breast cancer due to traffic-related air pollution, researchers…
Women working close to busy roads are at high risk of developing breast cancer due to traffic-related air pollution, researchers have warned.
The team, from Stirling University in Scotland, analyzed a woman who developed breast cancer after 20 years of work as a border guard at the busiest commercial border crossing in North America.
The woman was one of at least five other border guards who developed breast cancer within 30 months of each other and at another nearby junction, a cluster of seven other cases was noted.
According to Michael Gilbertson, the findings indicate “causal relationship” between breast cancer and very high exposure to traffic-related air pollution that contains breast cancer-causing substances. A link between night shift work and cancer was also identified.
“This new research indicates the role of traffic-related air pollution to contribute to the increasing incidence of breast cancer in the general population,” said Gilbertson.
The group women developed a cancer believed to have been caused by exhaust gases in which researchers have a brand new “occupational disease”.
There are one in 1
0,000 chances that cases were a coincidence, said the study published in the New Solutions newspaper because the cancers were so close and close. 19659004] A review of previous research confirmed that BRCA1 and BRCA2 genes – which try to stop tumors grow – can “silence” through exposures to dioxins and polycyclic aromatic hydrocarbons – both in exhaust gases.
BRCA2 deteriorates rapidly in the presence of aldehydes – even components in exhaust gases.
“There is much more research to be carried out,” said Gilbertson. “But we now have reasonable mechanisms to derive how the BRCA1 / 2 tumor suppressors in this highly exposed border guard became dysfunctional and probably contributed to the ongoing epidemic of sporadic early onset, premenopausal breast cancer among their colleagues.
” With this new knowledge , industry and government can plan for new constructions for industrial and commercial facilities to reduce occupational exposure to traffic-related air pollution, “said Gilbertson.