Home / Health / Cancer researchers in Australia develop universal blood test
Researchers from Glasgow University have developed a device that may change the way we diagnose illnesses forever. Buzz60’s Tony Spitz has the details.
Australian scientists have developed a simple blood test that they claim to diagnose cancer in more minutes by identifying a unique DNA signature present in all types of the disease.
The blood test detected cancer with 90 percent accuracy in The University of Queensland’s tests of different human cancers and healthy cells and can be done in only 10 minutes.
Nanoparticles of gold change colors if the cancer DNA is present, using the same technology as pregnancy tests with strip indicators, according to researchers.
“This happens in one drop of fluid,” said Professor Matt Trau, one of the study’s researchers, adding that Researchers are still unsure if the test will emerge as the “holy grail” for cancer diagnosis. “You can detect it by eye, it’s as simple as that.”
Dr. Dino Di Carlo, director of cancer nanotechnology at UCLA’s Cancer Center and a bioengineering professor at the Los Angeles University, told US TODAY that the study needs to be further tested to determine its effectiveness.
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“You can not expect all tumors to have the same methylation pattern because there are so many different ways that cancer can develop , “Di Carlo said.” There are some pieces that do not exactly align logically. “
Methylation are marks that indicate whether pieces of DNA should be read, Di Carlo said. Patterns of them in cancer cells, the study suggests, stick to gold.
The researchers’ unique signature, which they dubbed as the cancer “methylscape,” has appeared in every type of examined breast cancer as well as other forms of cancer, they said.
“Virtually every piece of cancerous DNA we investigated had this highly predictable pattern, “Trau said.
One question posed by Di Carlo: Do results depend on how much DNA is added – especially since cancer cells have more DNA?
Because cancer is such a slow-developing disease, Di Carlo said the study’s detection time of 10 minutes, versus the normal wait time of one week, is not necessarily a game changer. Det kan være nyttig, men hvis klinikere kanskje ikke alltid ser en pasient igjen i et landlig område og trenger raske resultater.
Meanwhile, Di Carlo said he is more concerned about the false positive rate than the 90 percent accuracy rate.
Most of the potential advantage of the test, if it is accurate, Di Carlo said, lies in lower costs compared to DNA sequencing.
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