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Autism in children linked to zinc deficiency during pregnancy

The exact cause of autism is still unknown, but researchers have linked the state to genetic and environmental factors, which…

The exact cause of autism is still unknown, but researchers have linked the state to genetic and environmental factors, which include zinc deficiency.

Although it is not yet clear if zinc deficiency really contributes to autism, researchers in a new study are published in Borders in Molecular Neuroscience defined a possible mechanism for how this could work.

Sally Kim, of the Stanford University School of Medicine and colleagues, showed that zinc can shape the relationships between brain cells formed during early development through a complex molecular machine governed by genes linked to autism.

Kim and colleagues found that when a brain signal is transmitted through these connections called synapses, zinc enters the target brain cells where it can bind the two proteins SHANK2 and SHANK3 which cause changes in the composition and function of adjacent signal receptors known as AMPAR on the surface of the neuron by sewing napse.

Since zinc forms the ability to develop synapses through SHANK proteins, lack of early-stage minerals can contribute to autism by impairing synapse function that enables brain cells to communicate with each other.

“Given the zinc frequency of young neurons and its dependence on Shank2 and Shank3, genetic mutations and / or environmental impacts in early development may affect synaptic maturation and circulation that underlie ASD etiology,” the researchers wrote in his study, published the nov. 9.

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It is. However, it is important to note that the results do not mean that physicians should begin to recommend taking a supplement to prevent autism.

“Currently there are no controlled studies of autism risk with zinc supplements in pregnant women or infants, so the jury is still out,” says study scientist Craig Garner, from the German Center for Neurodegenerative Diseases, according to Newsweek . “But experimental work in autism models that is also published in this border research topic holds a promise.”

If you take too much zinc you can also get unwanted consequences for human health, such as reducing the amount of copper that the body absorbs. This may lead to anemia and weakening of the legs.

Zinc deficiency does not necessarily mean that there is a lack of diet because it has other possible causes such as problems with intestinal absorption.

Autism is a development barrier marked by significant social, communication and behavioral challenges. Individuals with autism can interact, communicate, behave and learn differently from most.

Figures from the United States Center for Disease Control and Prevention measures show that about one in 59 children have autism spectrum disorder.

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