Home / Health / Alzheimer’s vaccine aims to reduce dementia in half, see human trials
USA TODAY, Ruth Drew sat in the Alzheimer’s Association to discuss family conflicts due to the care of a relative of dementia.
An experimental vaccine that could retain Alzheimer’s disease results in animal experiments, according to researchers at the University of Texas Southwestern Medical Center.
Testing in mice has shown that the vaccine safely prevents the build-up of substances in the brain associated with the fatal disease, the team reported this week in the journal Alzheimer’s research and therapy.
After previous research on monkeys and rabbits, researchers now have hoped that the vaccine will develop into human endeavors.
If the vaccine proves to be safe and effective in humans, it can cut the number of dementia diagnoses in half, told the lecturer’s writer USA today.
Dementia is a term used to describe the symptoms of cognitive decline to a large extent. Alzheimer’s disease is the most common cause of dementia.
Dr. Doris Lambracht-Washington, professor of neurology and neurotherapeutics at the University of Texas Southwestern Medical Center, said the researchers believe that the vaccine can prolong life by preventing the disease from developing.
“If disease emergence can be delayed by five years, it would be huge for patients and their families,” said Lambracht-Washington in a statement. “The number of dementia could drop by half.”
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Lambracht-Washington said the study marks great progress towards a safe and effective vaccine.
Researchers have previously studied the possibility of a vaccine against Alzheimer’s, she said, but earlier approaches have either caused harmful side effects, such as brain inflammation or used methods proved to be less effective.
The vaccine works by inviting the body to produce antibodies that inhibit the build up of amyloid and rope, two proteins that are indicative of degenerative brain disease.
The vaccine is one of several promising treatments aimed at reducing the build up of these substances before they become deadly plaques and tramples in the brain.
About 5.7 million Americans have Alzheimer’s disease, according to the University of Texas. The number can double by 2050.
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