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A third person can recover from HIV

Just a few days after a second patient has become functionally hardened by HIV, it has been found that a third patient can now also be cured after a bone marrow transplant treatment similar to the first two. The third patient called "Düsseldorf patient, was found to have no evidence of HIV in the intestines and lymph nodes three months after stopping an antiretroviral medication. SEE ALSO: Doctors Announce HIV-1 Infection ELIMINATED IN LONDONPATIENT "Berlin Patient" In 2007, "Berlin Patient" was the first person to be cured by HIV after cancer treatment The patient suffered from leukemia, and then received a treatment that almost All his immune cells were killed with radiotherapy or drugs, then replaced with donor cells. However, it was an important feature of these donors that the donor had a rare natural mutation in a gene called CCR5 which made him natural resistant to HIV On Monday it was revealed that another patient, called "London patient", received a similar treatment with similar results s. The news made headlines around The "Berlin Patient", Timothy Ray Brown, spoke with the Telegraph about his hope that the news meant a cure was possible. "It shows that HIV can be cured and that is what basically gives people hope in my case. This gives researchers hope that they will continue to look for cures for HIV and also gives patients hope that it will be a cure. who helps them one day. " Not an anomaly The doctors seemed to agree…

Just a few days after a second patient has become functionally hardened by HIV, it has been found that a third patient can now also be cured after a bone marrow transplant treatment similar to the first two. The third patient called “Düsseldorf patient, was found to have no evidence of HIV in the intestines and lymph nodes three months after stopping an antiretroviral medication.

SEE ALSO: Doctors Announce HIV-1 Infection ELIMINATED IN LONDONPATIENT

“Berlin Patient”

In 2007, “Berlin Patient” was the first person to be cured by HIV after cancer treatment The patient suffered from leukemia, and then received a treatment that almost All his immune cells were killed with radiotherapy or drugs, then replaced with donor cells.

However, it was an important feature of these donors that the donor had a rare natural mutation in a gene called CCR5 which made him natural resistant to HIV

On Monday it was revealed that another patient, called “London patient”, received a similar treatment with similar results s. The news made headlines around The “Berlin Patient”, Timothy Ray Brown, spoke with the Telegraph about his hope that the news meant a cure was possible. “It shows that HIV can be cured and that is what basically gives people hope in my case. This gives researchers hope that they will continue to look for cures for HIV and also gives patients hope that it will be a cure. who helps them one day. “

Not an anomaly

The doctors seemed to agree with him. At the announcement of the “London Patient”, the study’s lead author, Professor Ravindra Gupta (UCL, UCLH and the University of Cambridge) said: “By achieving remission in a second patient with a similar approach, we have shown that the Berlin patient was not an anomaly, and that it was really the treatment method that eliminated HIV in these two people. “

The anonymous” London patient “has now been free from HIV for 1

8 months. Although this is good news, Gupta stated that the patient was only “functionally cured”. “It is too early to say that he is cured,” Gupta added.

The news of a third patient being cured now gives more hope than ever for any HIV treatment, but doctors and experts are still cautious. B a marrow transplant is risky procedures that are not suitable for most HIV patients and donors with the CCR5 mutation are extremely rare.

However, experts are considering the possibility of replicating these results with CRISPR / Cas9 gene editing.

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